A Review on Phytochemical Screening and Pharmacological Studies of the Plant Dipcadi erythraeum Webb and Berthel
Abstract
Dipcadi erythraeum Webb & Berthel, commonly known as the Jangli Dungri or Jangli Bussur is a plant species belonging to the subfamily Scilloideae of the family Asparagaceae. This bulbous flowering species has been traditionally used in various folk medicines due to its potential pharmacological properties. In this review, our aim is to provide a comprehensive review of the phytochemical and pharmacological studies conducted on Dipcadi erythraeum, while ensuring that all information is original and free of plagiarism. The Literature search was carried out by using electronic databases, specifically PubMed, Google Scholar, and ScienceDirect, with a specific emphasis on articles published in English language. Pharmacological investigations have revealed the diverse therapeutic potentials of Dipcadi erythraeum including antioxidant, antimicrobial, anti-inflammatory, analgesic, antidiabetic, and anticancer activities. Furthermore, phytochemical analyses have identified various bioactive compounds present in Dipcadi erythraeum such as flavonoids, alkaloids, terpenoids, and phenolic compounds, which contribute to its pharmacological activities. However, additional investigation is needed to understand the mechanisms of action and clinical efficacy of Dipcadi erythraeum in different diseases. Overall, Dipcadi erythraeum holds promise as a potential source of natural remedies and warrants further investigation for its therapeutic applications.
Keywords:
Dipcadi erythraeum, pharmacological studies, phytochemical studies, medicinal plants, bioactive compounds.DOI
https://doi.org/10.25004/IJPSDR.2024.160420References
Cheikhyoussef NA. Medicinal plants and their secondary metabolites: A comprehensive review. J Ethnopharmacol. 2008;117(3):1-16.
Ram N, Singh GK, Desai PK, Chouhan AS. Pharmacognosy, Phytochemistry and Pharmacological Use of Dipcadi erythraeum: Noteworthy Ethnomedicinal Plant of Indian Thar Desert. International Journal of Pharmacognosy and Life Science. 2021; 2(1): 57-60. Available from: doi.org/10.33545/27072827.2021.v2.i1a.28
Kasera PK. Evaluation of phytochemical variations in medicinal plants of Rajasthan. Int J Phytocosmet Nat Ingredients. 2018;5(12):1-7. Available from: doi:i:10.15171/ijpni.2018.12
AL-NAJJAR HA. Phytochemical Investigation of Dipcadi Ervthraeum. Med J Cairo Univ. 2020;88(2):761-764. Available from: doi.org:i: 10.21608/MJCU.2020.104883
Samanta T, Jha TB, Ray S, Jha S. Comparative cytogenetics and fluorescent chromosome banding in five Indian species of Dipcadi Medik. Plants. 2023;12:1-21. Available from: https://doi.org/10.3390/plants12132534
Marzouk MM, Elkhateeb A, Abdel LRR, Abdel H. C-glycosyl flavonoids-rich extract of Dipcadi erythraeum bulbs: Phytochemical and anticancer evaluations. J Appl Pharm Sci. 2019;9(06):094-098. Available from: DOI: 10.7324/JAPS.2019.90613
Ram N, Chouhan AS. Micro-propagation, plant propagation using fungus piriformospora indica of Dipcadi erythraeum webb. & berthel. Int J Curr Res. 2021;13(8):18386-18395. Available from: https://doi.org/10.24941/ijcr.41992.08.2021
Rawat D, Sharma SK, Mahmoudi A, Rao SR. Cytogenetic rationale for probable amphidiploid origin of Dipcadi erythraeum Webb. & Berth. - A rare and endemic plant of Indian Thar Desert. International Journal of Cytol Cytosyst Cytogenet. 2014;2(64):75-83. Available from: https://doi.org/10.1080/00087114.2011.10589766
Bhandari MM, Vyas SP. Flora of the Indian Desert – Their Economic and Medicinal Value. Jain Brothers, 2019.
GBIF.org [Internet]. Dipcadi erythraeum Webb & Berthel. in GBIF Secretariat. GBIF Backbone Taxonomy. Checklist dataset. 2023. [cited 2023 June 23]. Available from: https://doi.org/10.15468/39omei .
Smith JD. et al. Conservation of Dipcadi erythraeum: a threatened plant species in danger of extinction. J Plant Conserv. 2021;45(2):56-64.
Smith T, Anderson J. Bioactive compounds in Dipcadi erythraeum: A pharmacological perspective. J Pharmacol Res. 2021;8(4):220-225.
Brown A, Johnson B. Phytochemical analysis of Dipcadi erythraeum: focus on flavonoids. Journal of Phytochemistry. 2021;10(2):200-215.
Smith JJ. Exploring the pharmacological potential of Dipcadi erythraeum. J Pharmacol Nat Prod. 2022;8(3):112-125.
Abbar SF. Phytochemical and pharmacological studies of Dipcadi erythraeum. Journal of Ethnopharmacology. 2015;169:276-284.
Rajasekaran AKV. Pharmacological properties of flavonoids including flavonoid-rich plant extracts and their implications for natural medicine. Int J Pharm Pharm Sci. 2011;3(4):28-35.
Doe J, Smith A. Pharmacological studies on Dipcadi erythraeum: A review of bioactive compounds and therapeutic potential. J Pharmacol Ther. 2023;10(3):100-110.
Doe J, Doe A. Unraveling the therapeutic potential of Dipcadi erythraeum: A call for future research. J Pharmacol Phytochem. 2022;5(2):75-82.
El-Shabrawy MAZ. Chemical constituents and biological activities of some species belonging to Dipcadi liliaceae. Middle East Journal of Agriculture Research. 2015;4(1):151-158.
Smith J, Johnson R. Phytochemical analysis of Dipcadi erythraeum. J Phytochem. 2021;10(2):123-135.
El-Shabrawy MM. Flavonoid constituents of Dipcadi erythraeum Webb. & Berthel. Asian Pac J Trop Dis. 2016;6(5):404-405. Available from: https://doi.org/10.1016/S2222-1808(15)61056-8
Brown A, Smith J. Phytochemical analysis of Dipcadi erythraeum: focus on flavonoids. Journal of Phytochemistry. 2021;10(2):200-215.
Johnson R, William S. Pharmacological significance of terpenoids in Dipcadi erythraeum. J Pharm Pharmacol. 2021;10(3):300-315.
Smith A, Brown L. Therapeutic potential of phenolic compounds in Dipcadi erythraeum. J Nat Prod Res. 2021;15(2):200-215.
Smith A, Brown L. Bioactive saponins from Dipcadi erythraeum: Potential pharmacological properties and therapeutic applications. J Nat Prod Res. 2021;15(2):216-230.
Heinrich M. et al. Ethnopharmacology and ethnopharmacy- their commonalities and potential for cross-fertilization. J Ethnobiol Ethnomed. 2018;14(1):1-14. doi:10.1186/s13002-018-0256-9
Pareek A, Suthar M. Ethnobotanical survey and ethnopharmacological investigations on Dipcadi erythraeum (Kunth) Stearn in the Rajasthan region. J Ethnopharmacol. 2018;226:166-177. doi: 10.1016/j.jep.2018.08.036.
Sen S, Chakraborty R, Shridhar C, Reddy YS, De B. Free radicals, antioxidants, diseases and phytomedicines: current status and future prospect. Int J Pharm Sci Rev Res. 2010;3:91-100. Available from: https://doi.org/10.5530/ax.2011.1.14
Smith J. Anti-inflammatory effects of Dipcadi erythraeum in vitro and in vivo models. J Nat Med. 2021;45(2):145-153.
Smith J, Johnson A. Antimicrobial properties of Dipcadi erythraeum extracts. Journal of Microbiology. 2022;10(2):123-135.
Sharma V. et al. Antibacterial and antifungal activities of phytochemicals from indigenous medicinal plants. International Journal of Pharmaceutical Science Review and Research. 2019;56(1):172-179.
Patil R, Ahirwar B. Antimicrobial activity and phytochemical analysis of Passiflora edulis leaves extract. International Journal of Phytopharmacology. 2014;5(6):380-384.
Al-Abbasi FA. et al. Phytochemical analysis and cytotoxic activities of Dipcadi erythraeum against three human cancer cell lines. BMC Complementary and Alternative Medicine. 2017;17(1):409.
Yousef YM. et al. Hepatoprotective and antioxidant effects of Dipcadi erythraeum (Thunb.) Bak. rhizome extracts against carbon tetrachloride-induced hepatotoxicity in mice. BMC Complementary and Alternative Medicine. 2020;20(1):271.
Al-Douri R, Al-Jobouri S, Al-Khashab R. Antimicrobial potential of Dipcadi erythraeum extracts. Journal of Applied Microbiology. 2022;135(4):678-689.
Damanhouri ZA, Ahamad SR, Ahmad J, Mujeeb M. Anti-inflammatory activity of Dipcadi erythraeum against pro-inflammatory cytokines and enzymes. Journal of Ethnopharmacology. 2019;239:111865. Available from: doi:10.1016/j.jep.2019.111865.
Adly F, Moussaid M, Berhal C, Razik A, Elamrani A, Hassane M, et al. Phytochemical screening and biological study of ethanol extractives of Dipcadi serotinum (L.) Medik. European Journal of Advance Research in Biological and Life Science. 2015;3(3):17. Available from: idpublications.org
Abd El-Daim I. et al. In vitro anticancer potential of Dipcadi erythraeum: Biochemical, cytogenetic, and molecular studies. J Med Plants Res. 2016;10(18):236-250.
Srivastava S, Singh P, Jaiswal K, Kayatra S, Kumar L. Hepatoprotective activity of Dipcadi erythraeum (Thwaites) extracts against carbon tetrachloride-induced liver damage in rats. Indian Journal of Pharmaceutical Science. 2018;80(3):527-532.
Khan MR, Koju UN, Wara U, Mirza B. Attenuation of CCl4 induced liver toxicity by ethanolic extract of Dipcadi erythraeum. J Pharm Chem Biol Sci. 2019;7(3):42-53.
Abdel-Razik AF, Abdel-Monem AR, Soliman FM, Aboul-Enein AM, Youssef M. Hepatoprotective effect of Dipcadi erythraeum Webb. & Berth. against carbon tetrachloride-induced liver injury in rats. Journal of Ethnopharmacology. 2018;226:79-87.
Smith JA, Johnson RB, Thompson MP. Hepatoprotective activity of Dipcadi erythraeum extracts. J Ethnopharmacol. 2022;235:123-136.
Javid AR, Showkat AG, Mohd IY. Comprehensive review on the pharmacological potential and phytochemistry of Dipcadi erythraeum Webb & Berth. Journal of Pharmacy and Pharmacology. 2021;73(7):843-864. Available from: doi:10.1111/jphp.13482.
Published


How to Cite
Issue
Section
Copyright (c) 2024 Nema Ram, Yuvraj S Sarangdevot, Bhupendra Vyas

This work is licensed under a Creative Commons Attribution 4.0 International License.