Unveiling the Pharmacological Spectrum of Justicia gendarussa: A Comprehensive Review

Authors

  • Pornima A Sontakke Department of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Pune, Maharashtra, India
  • Vaishnavi P Patil Department of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Pune, Maharashtra, India
  • Pavankumar P Wankhade Department of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Pune, Maharashtra, India
  • Niraj S Vhyawahare Department of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Pune, Maharashtra, India

Abstract

Justicia gendarussa Burm. f (J. gendarussa) is a flora part of Acanthaceae family, is a herbal remedy localized to numerous regions of Asia, which has been used since ancient times for its traditionally claimed pharmacological activities. J. gendarussa is a fast-developing bush that discovered in the tropical shady and moist places. Mostly this plant is found in China, hence also known as Chinese medicinal plant. Over the past few years, it has gathered significant attention due to its diverse pharmacological activities and rich chemical composition. Pharmacological investigations have revealed that J. gendarussa possesses a broad spectrum of biological activities, comprising, although not restricted to anti-HIV, anti-inflammatory, analgesic, anxiolytic, anti-microbial, hepatoprotective, anti-fungal, antioxidant, larvicidal, anthelmintic and antiarthritic. Furthermore, chemical analyses of J. gendarussa have identified a wide array of bioactive constituents, like alkaloids, flavonoids, terpenoids, phenols, carbohydrates and fatty acids. These phytochemicals play pivotal roles in mediating the observed pharmacological activities and hold promise for the creation of novel medications or supplements targeting the various health conditions. This review focuses on the pharmacological profile, bioactive components, and ethanobotanical significance of J. gendarussa. This inclusive assessment provides an extensive study of the current state of research on J. gendarussa, encompassing its pharmacological effects and chemical constituents. By consolidating existing knowledge, scholars and practitioners alike can benefit greatly from this review, fostering advanced exploration of this remarkable plant species for therapeutic purpose.

Keywords:

Justicia gendarussa; , chemical constituents, plant part, morphology, activity, pharmacological

DOI

https://doi.org/10.25004/IJPSDR.2024.160421

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Published

30-07-2024
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“Unveiling the Pharmacological Spectrum of Justicia Gendarussa: A Comprehensive Review”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 16, no. 4, July 2024, pp. 716-24, https://doi.org/10.25004/IJPSDR.2024.160421.

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How to Cite

“Unveiling the Pharmacological Spectrum of Justicia Gendarussa: A Comprehensive Review”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 16, no. 4, July 2024, pp. 716-24, https://doi.org/10.25004/IJPSDR.2024.160421.

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