2023. Design, Optimization and Characterization of Metformin Hydrochloride Loaded Biodegradable Microspheres using Box Behnken design for Local Delivery in Periodontitis. International Journal of Pharmaceutical Sciences and Drug Research. 15, 3 (May 2023), 310–316. DOI:https://doi.org/10.25004/IJPSDR.2023.150311.