UNCOVERING THE DIURETIC POTENTIAL OF ABUTILON HIRTUM LEAVES EXTRACT IN WISTAR ALBINO RATS
Abstract
Traditional medicine has long used plants with presumed diuretic properties, and there is increasing scientific interest in validating these remedies. Abutilon hirtum, a plant commonly used in traditional medicine, is being studied for its potential therapeutic benefits as a natural alternative to synthetic diuretics, which can cause side effects. The present study was designed to evaluate the diuretic activity of the leaves of Abutilon hirtum. Methanol was used as solvents for the Soxhlet extraction process. Wistar albino rats were divided into five groups, each containing six animals. These groups included a control group, a standard group, and test groups administered with 150, 300, and 450 mg/kg body weight of methanolic extracts. Diuretic activity was assessed using the lipschitz test. Diuretic activity was assessed using the lipschitz test. The results were evaluated based on urinary excretion of electrolytes, total urine volume, pH, diuretic effect, lipschitz value, saluretic index, and natriuretic index. At the higher dose, AHME showed significant increase in electrolyte excretion, urine volume and pH values compared to the control group. The leaves of Abutilon hirtum demonstrated significant diuretic activity with a lipschitz value of 2.35.
Keywords:
Abutilon hirtum, folkore, lipschitz modelDOI
https://doi.org/10.25004/References
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