NEW FLUORIMETRIC METHOD OF DETERMINATION FOR LISINOPRIL DOSAGE FORMS
Abstract
New fluorimetric analytical method which is simple, accurate, precise, specific is developed for determination of Lisinopril. The fluorimetric determination of Lisinopril is based on the formation of complex between Lisinopril and Fluorescien, measured at excitation wavelength of 366 nm and emission wavelength of 475 nm. Linearity was observed in the range of 0.03 – 0.15 µg ml-1. The fluorimetric method shows regression coefficient of 0.99971, and Relative Standard Deviation 0.527. Tablet dosage forms were estimated were complied with percentage recovery studies of 99-100 %. The method was validated for linearity, precision, accuracy, specificity and statistically expressed.
Keywords:
Lisinopril, Fluorescien, Coupling reaction, FluorimetryDOI
https://doi.org/10.25004/IJPSDR.2010.020304References
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17. Ersa SA, Lale E, Olcay S. A new spectrofluorimetric method for the determination of lisinopril in tablets. IL Farmaco 2003;58:165-168.
18. El-Yazbi, FA Abdine, HH, Shaalan RA. Spectrophotometric and spectrofluorometric methods for the assay of lisinopril in single and multicomponent pharmaceutical dosage forms. J Pharm Biomed Anal. 1999; 19: 819-827.
19. Sagirli O, Ersoy L. An HPLC method for the determination of lisinopril in human plasma and urine with fluorescence detection. J Chromatogr. 2004; 809(1): 159-165.
20. Ivanovic D, M Medenica, B. Jancic, N Knezevic, A Malenovic, J Milic.. Validation of an analytical procedure for simultaneous determination of hydrochlorothiazide, lisinopril, and their impurities. Acta Chromatogr, 2007; 18.
21. Yuan AS, Gilbert JD. Time-resolved fluoroimmunoassay for the determination of lisinopril and enalaprilat in human serum. J Pharm Biomed Anal.1996; 14:773-81.
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2. Indian Pharmacopoeia. Ministry of Health and Family Welfare New Delhi, 2007, 2, pp. 1306-08
3. British Pharmacopoeia. Stationery Office Books (TSO) London, United Kingdom, 2005, 2, pp. 1199.
4. United States Pharmacopoiea-USP-24, NF-19, Asian Edition, United States Pharmacopoeial Convention, INC. Twin brook Parkway, Rockville, MD, U.S.A. 2000, pp. 979.
5. Basavaiah K, Tharpa K, Salmara GH, Basavaiah VK. Spectrophotometric Determination of Lisinopril in Pharmaceuticals Using Ninhydrin- a Modified Approach. J Food Drug Anal.2009; 17( 2):93-99.
6. Devi PA, Mallikarjuna Rao GPV, Krishna Prasad KMM, Sastry C SP. Four simple spectrophotometric determinations of lisinopril in pure state and in tablets. Indian J Pharm Sci 2003; 65(3):296-99.
7. Paraskevas JG, Atta Politou, Koupparis M. Spectrophotometric determination of lisinopril in tablets using 1-fluoro-2, 4-dinitrobenzene reagent. J Pharm Biomed Anal. 2002; 29(5):865-72.
8. Abdel Razak .Belal OSF, Bedair MM, Barakat NS, Haggag RS. Spectrophotometric and polarographic determination of enalapril and lisinopril using 2, 4-dinitrofluorobenzene. J Pharm Biomed Anal.2003; 31(4):701-711.
9. Fawzy A, El-Yazbi Heba H, Abdine, Rasha A, Shaalan. Spectrophotometric and spectrofluorometric methods for the assay of lisinopril in single and multicomponent pharmaceutical dosage forms. J Pharm Biomed Anal.1999; 19:819–27.
10. Ali A, El-Emama, Steen Honore, Hansen Mohamed A, Moustafa, Saadia M, El-Ashry Dina T, El-Sherbiny. Determination of lisinopril in dosage forms and spiked human plasma through derivatization with 7-chloro-4-nitrobenzo-2-oxa-1, 3-diazole (NBD-Cl) followed by spectrophotometry or HPLC with fluorimetric detection. J Pharm Biomed.Anal. 2004; 34:35–44.
11. El-Gindy A, Ashour A, Abdel-Fattah L, Shabana MM. Spectrophotometric, septrofluorimetric and LC determination of lisinopril. J Pharm Biomed. Anal.2001; 25:913-22.
12. Asad Raza, Tariq Mahmood Ansaria, Atta-ur-Rehmanb. Spectrophotometric Determination of Lisinopril in Pure and Pharmaceutical Formulations. J Chine Chem Soci.2005; 52:1055-59.
13. Jain HK. Agrawal RK. Spectrophotometric method for simultaneous estimation of amlodipine besylate and lisinopril in tablets. Indian Drugs. 2000; 37(4):196-99.
14. Shinde V, Trivedi A, Upadhayay PR, Gupta NL, Kanase DG, Chikate R. Identification of a new impurity in lisinopril. J Pharm Biomed. Anal. 2007; 43; (1): 381-86.
15. Panzade, PD. K.R. Mahadik. Simultanous spectrophotometric estimation of Lisinopril and hydrochlorothiazide from combined dosage forms. Indian Drugs.1999;36(5):321-23
16. Durisehvar O, Hulya S. Determination of lisinopril from pharmaceutical preparations by derivative UV spectrophotometry. J Pharm Biomed Anal.1999; 21:691–95.
17. Ersa SA, Lale E, Olcay S. A new spectrofluorimetric method for the determination of lisinopril in tablets. IL Farmaco 2003;58:165-168.
18. El-Yazbi, FA Abdine, HH, Shaalan RA. Spectrophotometric and spectrofluorometric methods for the assay of lisinopril in single and multicomponent pharmaceutical dosage forms. J Pharm Biomed Anal. 1999; 19: 819-827.
19. Sagirli O, Ersoy L. An HPLC method for the determination of lisinopril in human plasma and urine with fluorescence detection. J Chromatogr. 2004; 809(1): 159-165.
20. Ivanovic D, M Medenica, B. Jancic, N Knezevic, A Malenovic, J Milic.. Validation of an analytical procedure for simultaneous determination of hydrochlorothiazide, lisinopril, and their impurities. Acta Chromatogr, 2007; 18.
21. Yuan AS, Gilbert JD. Time-resolved fluoroimmunoassay for the determination of lisinopril and enalaprilat in human serum. J Pharm Biomed Anal.1996; 14:773-81.
22. Gotti R, Andrisano V, Cavrini V, Bertucci C, Furlanetto S. Analysis of ACE-inhibitors by CE using alkylsulfonic additives. J Pharm Biomed Anal. 2000; 22:423-31.
Published
01-07-2010
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“NEW FLUORIMETRIC METHOD OF DETERMINATION FOR LISINOPRIL DOSAGE FORMS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 2, no. 3, July 2010, pp. 182-7, https://doi.org/10.25004/IJPSDR.2010.020304.
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How to Cite
“NEW FLUORIMETRIC METHOD OF DETERMINATION FOR LISINOPRIL DOSAGE FORMS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 2, no. 3, July 2010, pp. 182-7, https://doi.org/10.25004/IJPSDR.2010.020304.
