PHYTOCHEMICAL EXAMINATION AND ANTIMICROBIAL ACTIVITY OF VARIOUS SOLVENT EXTRACTS AND THE SELECTED ISOLATED COMPOUNDS FROM ROOTS OF TRAGIA INVOLUCRATA LINN.
Abstract
A large number of medicinal plants have been used for years in daily life to combat diseases, world over. Presently herbs, embodied with due importance in healthcare system, create a herbal renaissance, spread with a greater speed throughout the world. The herbal products today symbolize safety in contrast to the synthetic drugs that are regarded as unsafe to human environment. Population rise, inadequate supply of drugs, prohibitive cost of treatments, side effects of several allopathic drugs and development of resistance to currently used drugs for infectious diseases, have led to increase emphasis on the use of plant materials as source of medicines for a wide variety of human ailments. It is therefore, essential to search for the efficacious plants of medicinal value for better manifestations. In the present study, the fresh roots of young matured plants of Tragia involucrata Linn. were selected for phytochemical and antimicrobial screening to justify the folklore uses of the plant parts in various microbial infections.
Keywords:
Tragia involucrata Linn, solvent extracts, phytochemical examination, isolated compounds, antimicrobial activityDOI
https://doi.org/10.25004/IJPSDR.2012.040108References
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19. Brasileiro G, Pizziolo VR, Raslan DS, Jamal CM, Silveira D. Antimicrobial and cytotoxic activities screening of some Brazilian medicinal plants used in Governador Valadares district, Beatriz. Brazilian J. Pharm. Sci. 2006; 42: 195-202.
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2. Leong YW, Harrison LJ, Powell AD. Phenanthrene and other aromatic constituents of Bulbophyllum vaginatum. Phytochemistry 1999; 50: 1237-1241.
3. Kovacs A, Vasas A, Hohmann J. Natural phenanthrenes and their biological activity. Phytochemistry 2008; 69:1084-1110.
4. Hussain MM, Rahman MS, Jabbar A, Rashid MA. Phytochemical and biological investigations of Albizzia lebbeck Benth. Bol. Latinoam. Caribe Plant. Med. Aromaticas. 2008; 7: 273-278.
5. Pateh UU, Haruna AK, Garba M, Iliya I, Sule IM, Abubakar MS, Ambi AA. Isolation of stigmasterol, β-sitosterol and 2-hydroxyhexadecanoic acid methyl ester from the rhizomes of Stylochiton lancifolius pyer and kotchy (Araceae). Nig. J. Pharm. Sci. 2009; 8: 19-25.
6. Harraz FM. Constituents of Euphorbia retusa. EJEAFChe. 2009; 8: 179-183.
7. Rattanachaikunsopon P, Phumkhachorn P. Contents and antibacterial activity of flavonoids extracted from leaves of Psidium guajava. J. Med. Plant. Res. 2010; 4: 393-396.
8. Arima H, Ashida H, Danno G. Rutin-enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteritidis. Biosci. Biotech. Biochem. 2002; 5: 1009-1014.
9. Almahyl HA, Rahmani M, Sukari MA, Ali AM. Investigation on the chemical constituents of the leaves of Ficus elastica Roxb. and their antimicrobial activity. Pertanika J. Sci. Technol. 2003; 11: 57-63.
10. Sato M, Tanaka H, Tani N, Nagayama M, Yamaguchi R. Different antibacterial actions of isoflavones isolated from Erythrina poeppigiana against methicillin-resistant Staphylococcus aureus. Lett. Appl. Microbiol. 2006; 43: 243-248.
11. Rashid F, Ahmed R, Mahmood A, Ahmad Z, Bibi N, Kazmi SU. Flavonoid Glycosides from Prunus armeniaca and the antibacterial activity of a crude extract. Arch. Pharm. Res. 2007; 30: 932-937.
12. Madan S, Singha GN, Kumar Y, Kohli K, Singha RM, Mir SR, Ahmadc S. A new flavanone from Flemingia strobilifera (L) R. Br. and its antimicrobial activity. Trop. J. Pharm. Res. 2008; 7: 921-927.
13. Okwu DE, Ukanwa N. Isolation, characterization and antibacterial activity screening of anthocyanidine glycosides from Alchornea cordifolia (Schumach. and Thonn.) Mull. Arg. Leaves. E- J. Chem. 2010; 7: 41-48.
14. Anonymous. Laboratory methodologies for bacterial antimicrobial susceptibility testing, OIE Terrestrial Manual- 2008, Chapter - 1.1.6: pp. 56-65.
15. Lalitha MK. Methods of antimicrobial susceptibility testing. Manual on antimicrobial susceptibility testing, pp. 6-20, 2008. Internet: http://www.scribd.com/ doc/9177676/ Manual-on-Antimicrobial-Susceptibility-Testing-Dr-MK-Lalitha.
16. Hostettmann K, Marston A. Search for new antifungal compounds from higher plants, Pure & App. Chem. 1994; 66: 2231-2234.
17. Nascimento GGF, Locatelli J, Freitas PC, Silva GL. Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria, Brazilian J. Microbiol. 2000; 31: 247-256.
18. Janovska D, Kubikova K, Kokoska L. Screening for antimicrobial activity of some medicinal plants species of traditional Chinese medicine. Czech J. Food Sci. 2003; 21: 107-110.
19. Brasileiro G, Pizziolo VR, Raslan DS, Jamal CM, Silveira D. Antimicrobial and cytotoxic activities screening of some Brazilian medicinal plants used in Governador Valadares district, Beatriz. Brazilian J. Pharm. Sci. 2006; 42: 195-202.
20. Zgoda JR, Porter JR. A convenient microdilution method for screening natural products against bacteria and fungi. Pharm. Biol. 2001; 39: 221-225.
21. Andrew JM. Determination of inhibitory concentration. J. antimicrob. chemother. 2001; 48: 5-16.
Published
01-01-2012
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“PHYTOCHEMICAL EXAMINATION AND ANTIMICROBIAL ACTIVITY OF VARIOUS SOLVENT EXTRACTS AND THE SELECTED ISOLATED COMPOUNDS FROM ROOTS OF TRAGIA INVOLUCRATA LINN”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 4, no. 1, Jan. 2012, pp. 44-48, https://doi.org/10.25004/IJPSDR.2012.040108.
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How to Cite
“PHYTOCHEMICAL EXAMINATION AND ANTIMICROBIAL ACTIVITY OF VARIOUS SOLVENT EXTRACTS AND THE SELECTED ISOLATED COMPOUNDS FROM ROOTS OF TRAGIA INVOLUCRATA LINN”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 4, no. 1, Jan. 2012, pp. 44-48, https://doi.org/10.25004/IJPSDR.2012.040108.
