A REVIEW ON MEDICINAL IMPORTANCE OF BASELLA ALBA L.
Abstract
The ethanobotanical properties of Basella alba have been reviewed in this article. Various parts of the plant are used for treatment of the diseases as well as for different healing activities of human beings as well as animals across the globe especially in India and China. Its use has been discovered as asperient, rubefacient and for catarrhl infections. Some of the compounds available especially in the plant are basellasaponins, kaempherol, betalin, etc. Several extracts like aqueous, chloroform, ethanol and petroleum has been used for different pharmaceutical activities.
Keywords:
Asperient, Basella alba, basellasaponins, extract rubefacientDOI
https://doi.org/10.25004/IJPSDR.2012.040204References
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2. Anandarajagopal K, Sudhahar D, Ajaykumar TV, Muthukumaran G. Evaluation of CNS Depressant Activity of Aerial Parts of Basella alba Linn. IJPI’S Journal of Pharmacology and Toxicology 2011; 1:5.
3. Daniyan SY, Muhammad HB. Evaluation of the antimicrobial activities and phytochemical properties of extracts of Tamaridus indica against some diseases causing bacteria. African Journal of Biotechnology 2008; 7(14): 2451-2453.
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6. Chou CT. The anti-inflammatory effect of Tripterygium wilfordii Hook F on adjuvant-induced paw edema in rats and inflammatory mediators release. Phytother Res. 1997; 11:152-154.
7. Saikia AP, Ryakala VK, Sharma P, Goswami P, Bora U. Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics. J Ethnopharmacol. 2006; 106:149-157.
8. Akhter S, Abdul H, Shawkat IS, Swapan KS, Mohammad SHC, Sanjay SS. A review on the use of non-timber forest products in beauty-care in Bangladesh. J Forestry Res. 2008; 19:72-78.
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10. Pascaline J, Charles M, George O, Lukhoba C, Ruth L N, Solomon D M. Ethnobotanical survey and propagation of some endangered medicinal plants from south Nandi district of Kenya. Journal of Animal & Plant Sciences 2010; 8(3): 1016- 1043.
11. Chifundera K. Livestock diseases and the traditional medicine In the Bushi area, Kivu province, democratic Republic of Congo. African Study Monographs 1998; 19(1): 13-3.
12. Ramu G, Krishna Mohan G, Jayaveera KN. Preliminary investigation of patchaippasali mucilage (Basella alba) as tablet binder. IJGP 2011; 5(1):24-27.
13. Rahmatullah M, Rahman A, Haque Z, Mollik AH, Emdad Ullah Miajee ZUM, Begum R, Rahman M, Nasrin D, Seraj S, Chowdhury AR, Khatun Z, Khatun A. A Survey of Medicinal Plants used by Folk Medicinal Practitioners of Station Purbo Para Village of Jamalpur Sadar Upazila in Jamalpur district, Bangladesh. American-Eurasian Journal of Sustainable Agriculture 2010; 4(2): 122-135.
14. Focho DA, Nkeng EAP, Lucha CF, Ndam WT, Afegenui A. Ethnobotanical survey of plants used to treat diseases of the reproductive system and preliminary phytochemical screening of some species of malvaceae in Ndop Central Sub-division, Cameroon. Journal of Medicinal Plants Research. 2009; 3(4): 301-3141.
15. Yasmin H, Kaiser MA,Rahman MM, Rahman MS, Rashid MA. Preliminary antibacterial activity of some indigenous plants. The Dhaka University Journal of Pharmaceutical Sciences 2009; 8: 61-66.
16. Jadhav VD, Mahadkar SD, Valvi SR. Documentation and ethnobotanical survey of wild edible plants from Kolhapur District. Recent Research in Science and Technology 2011; 3(12): 58-63.
17. Yang RY, Lin S, Kuo G. Content and distribution of flavonoids among 91 edible plant species. Asia Pac J Clin Nutr. 2008; 17(S1): 275-279.
18. Toshiyuki M, Kazuhiro H, Masayuki Y. Medicinal foodstuffs. XXIII. Structures of new oleananetype triterpene oligoglycosides, basellasaponins A, B, C, and D, from the fresh aerial parts of Basella rubra L. Chem Pharm Bull. 2001; 49:776-779.
19. Khare CP. Indian medicinal plants: an illustrated dictionary. USA: Springer Science Business Media, 2007.
20. Maisuthisakul P, Ritthiruangdej PS. Relationship between antioxidant properties and chemical composition of some Thai plants. J Food Compos Anal. 2008; 21:229-240.
21. Glassgen WE, Metzger JW, Heuer S, Strack D. Betacyanins from fruits of Basella rubra. Phytochemistry 1993; 33:1525-1527.
22. Palanuvej C, Hokputsa S, Tunsaringkarn T, Ruangrungsi N. In vitro glucose entrapment and alpha-glucosidase inhibition of mucilaginous substances from selected Thai medicinal plants. Sci Pharm. 2009; 77:837-849.
23. Haq QN, Awal A, Chowdhury MK, Khan NA. Water-soluble polysaccharides from the leaves of Basella rubra. Sci Res. 1969; 6:63-6.
24. Jani GK, Shah DP, Jain VC, Patel MJ, Vithalani DA. Evaluating mucilage from Aloe Barbadensis Miller as a pharmaceutical excipient for sustained release matrix tablets. Pharm Technol. 2007; 31:90-98.
25. Olajire AA, Azeez L. Total antioxidant activity, phenolic, flavonoid and ascorbic acid contents of Nigerian vegetables, African Journal of Food Science and Technology 2011; 2(2): 022-029.
26. Barbosa-Filho JM, Alencar AA, Nunes XP, Tomaz ACA, Sena-Filho JG, Athayde-Filho PF, Silva MS, Souza MFV, da-Cunha EVL. Sources of alpha-, beta-, gamma-, delta- and epsilon-carotenes: A twentieth century review, Brazilian Journal of Pharmacognosy 2008; 18(1): 135-154.
27. Schmidt DR, MacDonald HA, Brockman FE. Oxalate and Nitrate Contents of Four Tropical Leafy Vegetables Grown at Two Soil Fertility Levels. Agronomy Journal 1970; 63(4): 559-561.
28. Palanuvej C, Ruangrungsi N. In Vitro Glucose Entrapment of Mucilaginous Substances from Various Medicinal Plants. Sci Pharm. 2009; 77: 837–849.
29. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, Bickford PC. Reversals of age-related declines in neuronal signal transduction cognitive and motor behavioral deficits with blueberry, spinach or strawberry dietry supplementation. The Journal of Neurosciences 1999; 8114-8121.
30. Pawlowicz P, Stachowiak G. Administration of natural anthocyanins derived from chokeberry retardation of idiopathic and preclamptic origin. Influence on metabolism of plasma oxidized lipoproteins: the role of autoantibodies to oxidize low density lipoproteins. Ginekol Pol. 2000; 71: 848-853.
31. Mas T, Susperregui J, Berké B, Chèze C, Moreau S, Nuhrich A, Vercauteren J. DNA triplex stabilization property of natural anthocyanins. Phytochemistry. 2000; 53: 679-687.
32. Pietrini F, Iannelli MA, Massacci A. Anthocyanin accumulation in the illuminated surface of maize Leaves enhances protection from photoinhibitory risk at low temperature without further limitation to photosynthesis. Plant, cell and environment, 2002; 25: 1251-1259.
33. Sivasankar V, Moorthi A, Sarathi Kannan D, Suganya devi P. Anthocyanin, and its antioxidant properties in Basella alba. Journal of Pharmacy Research. 2011; 4(3): 800-806.
34. Siriwatanametanon N, Fiebich BL. Efferth T, Prieto-Garcia JM, Heinrich M. Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities. J. Ethnopharmacol. 2010; 130(2): 196-207.
35. Premakumari KB, Ayesha Siddiqua, Shanaz Banu, Josephine J, Leno Jenita, Bincy Raj. Comparative Antimicrobial Studies of Methanolic Extract of Muntingia calabura, Basella alba and Basella rubra Leaves. Research Journal of Pharmacognosy and Phytochemistry. 2010; 2(3): 246-248.
36. Kumar V, Bhat ZA, Kumar D, Bohra P, Sheela S. In-vitro anti-inflammatory activity of leaf extracts of Basella Alba Linn. Var. Alba. International Journal of Drug Development and Research 2011; 3(2): 176-179.
37. Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hossain MI, Fuchs GJ, Brown KH. Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total -body vitamin A stores in Bangladeshi men. The American Journal of clinical nutrition 2004; 80(3): 705-714.
38. Phadungkit M, Somdee T, Kangsadalampai K. Phytochemical screening, antioxidant and antimutagenic activities of selected Thai edible plant extracts. Journal of Medicinal Plants Research 2012; 6(5): 662-666.
39. Bamidele O, Akinnuga AM, Olorunfemi JO, Odetola OA, Oparaji CK, Ezeigbo N. Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats. African Journal of Biotechnology 2010; 9(41): 6952-6955.
40. Nantia EA, Travert C, Manfo Faustin-Pascal T, Carreau S, Monsees TK, Moundipa PF. Effects of the Methanol Extract of Basella alba L (Basellaceae) on Steroid Production in Leydig Cells. Int J Mol Sci. 2011; 12: 376-384.
41. Rodda R, Kota A, Sindhuri T, Kumar SA, Gnananath K. Investigation on anti-inflammatory property of Basella alba Linn leaf extract. International Journal of Pharmacy and Pharmaceutical Sciences 2012; 4(1): 452-454.
2. Anandarajagopal K, Sudhahar D, Ajaykumar TV, Muthukumaran G. Evaluation of CNS Depressant Activity of Aerial Parts of Basella alba Linn. IJPI’S Journal of Pharmacology and Toxicology 2011; 1:5.
3. Daniyan SY, Muhammad HB. Evaluation of the antimicrobial activities and phytochemical properties of extracts of Tamaridus indica against some diseases causing bacteria. African Journal of Biotechnology 2008; 7(14): 2451-2453.
4. Kumar P. INDIAN SPINACH, Basella alba (PUI) succulent, branched, smooth, twining herbaceous vine. Best Nutrition, 2010.
5. Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hassain MI, Fuchs GJ, Brown KH. Daily consumption of Indian spinach (B. alba) or sweet potatoes has positive effect on total-body vitamin A store in Bangladeshi men. Am J Clin Nutr. 2004; 80(3): 705-714.
6. Chou CT. The anti-inflammatory effect of Tripterygium wilfordii Hook F on adjuvant-induced paw edema in rats and inflammatory mediators release. Phytother Res. 1997; 11:152-154.
7. Saikia AP, Ryakala VK, Sharma P, Goswami P, Bora U. Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics. J Ethnopharmacol. 2006; 106:149-157.
8. Akhter S, Abdul H, Shawkat IS, Swapan KS, Mohammad SHC, Sanjay SS. A review on the use of non-timber forest products in beauty-care in Bangladesh. J Forestry Res. 2008; 19:72-78.
9. Premalatha B, Rajgopal G. Cancer-an ayurvedic perspective. Pharmacol Res. 2005; 51:19-30.
10. Pascaline J, Charles M, George O, Lukhoba C, Ruth L N, Solomon D M. Ethnobotanical survey and propagation of some endangered medicinal plants from south Nandi district of Kenya. Journal of Animal & Plant Sciences 2010; 8(3): 1016- 1043.
11. Chifundera K. Livestock diseases and the traditional medicine In the Bushi area, Kivu province, democratic Republic of Congo. African Study Monographs 1998; 19(1): 13-3.
12. Ramu G, Krishna Mohan G, Jayaveera KN. Preliminary investigation of patchaippasali mucilage (Basella alba) as tablet binder. IJGP 2011; 5(1):24-27.
13. Rahmatullah M, Rahman A, Haque Z, Mollik AH, Emdad Ullah Miajee ZUM, Begum R, Rahman M, Nasrin D, Seraj S, Chowdhury AR, Khatun Z, Khatun A. A Survey of Medicinal Plants used by Folk Medicinal Practitioners of Station Purbo Para Village of Jamalpur Sadar Upazila in Jamalpur district, Bangladesh. American-Eurasian Journal of Sustainable Agriculture 2010; 4(2): 122-135.
14. Focho DA, Nkeng EAP, Lucha CF, Ndam WT, Afegenui A. Ethnobotanical survey of plants used to treat diseases of the reproductive system and preliminary phytochemical screening of some species of malvaceae in Ndop Central Sub-division, Cameroon. Journal of Medicinal Plants Research. 2009; 3(4): 301-3141.
15. Yasmin H, Kaiser MA,Rahman MM, Rahman MS, Rashid MA. Preliminary antibacterial activity of some indigenous plants. The Dhaka University Journal of Pharmaceutical Sciences 2009; 8: 61-66.
16. Jadhav VD, Mahadkar SD, Valvi SR. Documentation and ethnobotanical survey of wild edible plants from Kolhapur District. Recent Research in Science and Technology 2011; 3(12): 58-63.
17. Yang RY, Lin S, Kuo G. Content and distribution of flavonoids among 91 edible plant species. Asia Pac J Clin Nutr. 2008; 17(S1): 275-279.
18. Toshiyuki M, Kazuhiro H, Masayuki Y. Medicinal foodstuffs. XXIII. Structures of new oleananetype triterpene oligoglycosides, basellasaponins A, B, C, and D, from the fresh aerial parts of Basella rubra L. Chem Pharm Bull. 2001; 49:776-779.
19. Khare CP. Indian medicinal plants: an illustrated dictionary. USA: Springer Science Business Media, 2007.
20. Maisuthisakul P, Ritthiruangdej PS. Relationship between antioxidant properties and chemical composition of some Thai plants. J Food Compos Anal. 2008; 21:229-240.
21. Glassgen WE, Metzger JW, Heuer S, Strack D. Betacyanins from fruits of Basella rubra. Phytochemistry 1993; 33:1525-1527.
22. Palanuvej C, Hokputsa S, Tunsaringkarn T, Ruangrungsi N. In vitro glucose entrapment and alpha-glucosidase inhibition of mucilaginous substances from selected Thai medicinal plants. Sci Pharm. 2009; 77:837-849.
23. Haq QN, Awal A, Chowdhury MK, Khan NA. Water-soluble polysaccharides from the leaves of Basella rubra. Sci Res. 1969; 6:63-6.
24. Jani GK, Shah DP, Jain VC, Patel MJ, Vithalani DA. Evaluating mucilage from Aloe Barbadensis Miller as a pharmaceutical excipient for sustained release matrix tablets. Pharm Technol. 2007; 31:90-98.
25. Olajire AA, Azeez L. Total antioxidant activity, phenolic, flavonoid and ascorbic acid contents of Nigerian vegetables, African Journal of Food Science and Technology 2011; 2(2): 022-029.
26. Barbosa-Filho JM, Alencar AA, Nunes XP, Tomaz ACA, Sena-Filho JG, Athayde-Filho PF, Silva MS, Souza MFV, da-Cunha EVL. Sources of alpha-, beta-, gamma-, delta- and epsilon-carotenes: A twentieth century review, Brazilian Journal of Pharmacognosy 2008; 18(1): 135-154.
27. Schmidt DR, MacDonald HA, Brockman FE. Oxalate and Nitrate Contents of Four Tropical Leafy Vegetables Grown at Two Soil Fertility Levels. Agronomy Journal 1970; 63(4): 559-561.
28. Palanuvej C, Ruangrungsi N. In Vitro Glucose Entrapment of Mucilaginous Substances from Various Medicinal Plants. Sci Pharm. 2009; 77: 837–849.
29. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, Bickford PC. Reversals of age-related declines in neuronal signal transduction cognitive and motor behavioral deficits with blueberry, spinach or strawberry dietry supplementation. The Journal of Neurosciences 1999; 8114-8121.
30. Pawlowicz P, Stachowiak G. Administration of natural anthocyanins derived from chokeberry retardation of idiopathic and preclamptic origin. Influence on metabolism of plasma oxidized lipoproteins: the role of autoantibodies to oxidize low density lipoproteins. Ginekol Pol. 2000; 71: 848-853.
31. Mas T, Susperregui J, Berké B, Chèze C, Moreau S, Nuhrich A, Vercauteren J. DNA triplex stabilization property of natural anthocyanins. Phytochemistry. 2000; 53: 679-687.
32. Pietrini F, Iannelli MA, Massacci A. Anthocyanin accumulation in the illuminated surface of maize Leaves enhances protection from photoinhibitory risk at low temperature without further limitation to photosynthesis. Plant, cell and environment, 2002; 25: 1251-1259.
33. Sivasankar V, Moorthi A, Sarathi Kannan D, Suganya devi P. Anthocyanin, and its antioxidant properties in Basella alba. Journal of Pharmacy Research. 2011; 4(3): 800-806.
34. Siriwatanametanon N, Fiebich BL. Efferth T, Prieto-Garcia JM, Heinrich M. Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities. J. Ethnopharmacol. 2010; 130(2): 196-207.
35. Premakumari KB, Ayesha Siddiqua, Shanaz Banu, Josephine J, Leno Jenita, Bincy Raj. Comparative Antimicrobial Studies of Methanolic Extract of Muntingia calabura, Basella alba and Basella rubra Leaves. Research Journal of Pharmacognosy and Phytochemistry. 2010; 2(3): 246-248.
36. Kumar V, Bhat ZA, Kumar D, Bohra P, Sheela S. In-vitro anti-inflammatory activity of leaf extracts of Basella Alba Linn. Var. Alba. International Journal of Drug Development and Research 2011; 3(2): 176-179.
37. Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hossain MI, Fuchs GJ, Brown KH. Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total -body vitamin A stores in Bangladeshi men. The American Journal of clinical nutrition 2004; 80(3): 705-714.
38. Phadungkit M, Somdee T, Kangsadalampai K. Phytochemical screening, antioxidant and antimutagenic activities of selected Thai edible plant extracts. Journal of Medicinal Plants Research 2012; 6(5): 662-666.
39. Bamidele O, Akinnuga AM, Olorunfemi JO, Odetola OA, Oparaji CK, Ezeigbo N. Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats. African Journal of Biotechnology 2010; 9(41): 6952-6955.
40. Nantia EA, Travert C, Manfo Faustin-Pascal T, Carreau S, Monsees TK, Moundipa PF. Effects of the Methanol Extract of Basella alba L (Basellaceae) on Steroid Production in Leydig Cells. Int J Mol Sci. 2011; 12: 376-384.
41. Rodda R, Kota A, Sindhuri T, Kumar SA, Gnananath K. Investigation on anti-inflammatory property of Basella alba Linn leaf extract. International Journal of Pharmacy and Pharmaceutical Sciences 2012; 4(1): 452-454.
Published
01-04-2012
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“A REVIEW ON MEDICINAL IMPORTANCE OF BASELLA ALBA L”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 4, no. 2, Apr. 2012, pp. 110-4, https://doi.org/10.25004/IJPSDR.2012.040204.
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“A REVIEW ON MEDICINAL IMPORTANCE OF BASELLA ALBA L”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 4, no. 2, Apr. 2012, pp. 110-4, https://doi.org/10.25004/IJPSDR.2012.040204.
