IN-VITRO ANTHELMINTIC ACTIVITY OF OLEANDRA MUSIFOLIA (BL.) PRESL. AGAINST HAEMONCHUS CONTORTUS

Authors

  • Kalpana Devi Rajesh Department of Botany and Microbiology, A.V.V.M. Sri Pushpam College, Bharathidasan University, Thanjavur- 613 503, Tamil Nadu, India
  • Nakulan Valsala Rajesh Department of Animal Husbandry, Institute of Veterinary Preventive Medicine, Ranipet, Vellore- 632 402, Tamil Nadu, India
  • Subramani Vasantha Department of Botany and Microbiology, A.V.V.M. Sri Pushpam College, Bharathidasan University, Thanjavur- 613 503, Tamil Nadu, India
  • Solomon Jeeva Research Centre in Botany, Scott Christian College, Manonmaniam Sundaranar University (Affiliated), Kanyakumari- 629 003, Tamil Nadu, India

Abstract

Ethanolic, aqueous and Petroleum ether extracts from the whole fern, Oleandra musifolia (Bl.) Presl. (Family-Oleandraceae) was investigated for anthelmintic activity against Haemonchus contortus, with varied drug concentration (25, 50, and 100) mg/ml and the time taken for paralysis and death of the worm was determined. The in-vitro anthelmintic activity was compared with standard reference drug Albendazole and control distilled water. The result showed ethanolic extract performed well to express the anthelmintic efficacy than aqueous and petroleum ether extracts and the standard Albendazole. However efficacy is better and directly proportional to the increase in varied drug concentration. The efficacy is determined as lesser time taken to cause paralysis and death of Haemonchus contortus as compared to standard reference drug.

Keywords:

Anthelmintic, Oleandra musifolia (Bl.) Presl, Fern, Haemonchus contortus

DOI

https://doi.org/10.25004/IJPSDR.2014.060413

References

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Published

01-10-2014
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How to Cite

“IN-VITRO ANTHELMINTIC ACTIVITY OF OLEANDRA MUSIFOLIA (BL.) PRESL. AGAINST HAEMONCHUS CONTORTUS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 6, no. 4, Oct. 2014, pp. 345-7, https://doi.org/10.25004/IJPSDR.2014.060413.

Issue

Volume 6, Issue 4, 2014

Section

Research Article

How to Cite

“IN-VITRO ANTHELMINTIC ACTIVITY OF OLEANDRA MUSIFOLIA (BL.) PRESL. AGAINST HAEMONCHUS CONTORTUS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 6, no. 4, Oct. 2014, pp. 345-7, https://doi.org/10.25004/IJPSDR.2014.060413.