Case Report Study of an Integrated Treatment Approach in Critical Case of Covid-19 Patient
Abstract
The world has seen various variants of coronavirus and attempting all the feasible options to combat this pandemic situation. By far, vaccination is the most remarkable approach in controlling the Pandemic. India is fighting against the delta variant of the second wave COVID-19. Meanwhile, World Health Organization has already warned about the initial stages of the third wave in all countries. Therefore, on considering the variants of coronavirus, no standard option of care is available to date. In this article, we present a case study on the clinical outcome of the integrated treatment approach in COVID-19 patients suffering from critical conditions. The patient with a history of coronavirus was advised of strict home quarantine and standard treatment of care for 14 days. She was brought to the COVID-19 healthcare center in an unconscious state by her family. On examination, she had a 79% oxygen saturation, heart rate 88 beats/minute and her laboratory findings: CRP 37.3(mg/dL), ESR 84(mm/hour), D-dimer 793(ng/mL), and RBS 158 mg/d. After receiving consent from her family members, we initiated the integrated treatment approach. It includes T-AYU-HM Premium 600mg, is a herbo-mineral formulation, and Acupen 600 mg thrice a day with modern medicines. By adhering to the treatment, she recovered completely within a one-month duration. Her HRCT report showed a significant reduction in lung involvement with ill-defined low-density ground-glass opacities and atelectatic bands in both lungs. The patient's vitals and laboratory parameters presented striking improvement. This case study provides information about the effect of the integrated treatment approach in critical COVID-19 cases.
Keywords:
Covid-19, T-AYU-HM Premium, D-Dimer, CRP, ESRDOI
https://doi.org/10.25004/IJPSDR.2022.140118References
Hippich M, Sifft P, Zapardiel-Gonzalo J, et al. A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave. Med (N Y). 2021; 2(5):571-572. doi:10.1016/j.medj.2021.03.019
Jain VK, Iyengar KP, Vaishya R. Differences between First wave and Second wave of COVID-19 in India. Diabetes Metab Syndr. 2021; 15(3):1047-1048. doi:10.1016/j.dsx.2021.05.009
Jalali SF, Ghassemzadeh M, Mouodi S, et al. Epidemiologic comparison of the first and second waves of coronavirus disease in Babol, North of Iran. Caspian J Intern Med. 2020; 11(Suppl 1):544- 550. doi:10.22088/cjim.11.0.544
Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study [published correction appears in Lancet Respir Med. 2020 Apr;8(4):e26]. Lancet Respir Med. 2020; 8(5):475-481. doi:10.1016/S2213-2600(20)30079-5
Tregoning JS, Flight KE, Higham SL, Wang Z, Pierce BF. Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape. Nat Rev Immunol. 2021; 21(10):626-636. doi:10.1038/s41577-021-00592-1
Desai AM, Desai H, Desai C and Patel M: An acute oral toxicity study of T-AYU-HM premium tablet in rats: an initiative for sickle cell anemia management. Int J Pharm Sci & Res 2020; 11(12): 6157-60. doi: 10.13040/IJPSR.0975-8232.11(12).6157-60.
Desai AM, Saraf MN, Desai C, Desai H and Dalal M: Clinical evaluation of T-AYU-HMTM in the management of sickle cell anemia. Int J Pharm Sci& Res. 2018; 9(8): 3573-78.
Desai A, Desai K, Desai H, Desai C, Desai R. Effectiveness Report of T-AYU-HM Premium and Onion Vaporization on Corona Positive Sickle Cell Anemia Patients: A Case Study. International Journal of Pharmaceutical Sciences Drug Research. 2021; 13(1):99-102. doi: https://doi.org/10.25004/IJPSDR.2021.130115
Desai AM, Desai HA, Desai RA, Merai AK, Desai C, Khan M, Paul A. Evaluation of Immunomodulatory effect of T-AYU-HM Premium in Experimental Animal Models. Int. J. Pharm. Sci. Drug Res. 2021; 13(4):432-437. DOI: 10.25004/IJPSDR.2021.130409
CTRI-http://ctri.nic.inCTRI/2020/08/027477
Murthy S, Gomersall CD, Fowler RA. Care for Critically ill patients with COVID-19. JAMA. 2020; 323(15):1499-1500. doi:10.1001/ jama.2020.3633
Chen T, Wu D, Chen H, Yan W, Yang D, Chen G et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study BMJ 2020; 368 :m1091 doi:10.1136/bmj.m1091
Canoglu K, Saylan B. Therapeutic dosing of low-molecular-weight heparin may decrease mortality in patients with severe COVID-19 infection. Ann Saudi Med. 2020; 40(6):462-468. doi:10.5144/0256- 4947.2020.462
Ahmed MH, Hassan A. Dexamethasone for the Treatment of Coronavirus Disease (COVID-19): a Review [published online ahead of print, 2020 Oct 31]. SN Compr Clin Med. 2020;1-10. doi:10.1007/ s42399-020-00610-8
Pan Y, Guan H, Zhou S, et al. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. Eur Radiol. 2020; 30(6):3306- 3309. doi:10.1007/s00330-020-06731-x
Oudkerk M, Büller HR, Kuijpers D, et al. Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands. Radiology. 2020; 297(1):E216-E222. doi:10.1148/radiol.2020201629
Francone M, Iafrate F, Masci GM, et al. Chest CT score in COVID-19 patients: correlation with disease severity and short-term prognosis. Eur Radiol. 2020; 30(12):6808-6817. doi:10.1007/ s00330-020-07033-y
Published

