Evaluation of In-vitro anti-inflammatory and antibacterial potential of methanolic leaf extracts of Elytranthe parasitica (L.) Danser (Loranthaceae) – A Hemiparasitic Angiosperm
Abstract
Elytranthe parasitica (L.) Danser is a hemiparasitic angiosperm shrub commonly called Macrosolen parasiticus and it is a member of the family Loranthaceae. The members of Loranthaceae are utilized globally in conventional medicine to cure a variety of ailments. The current study aimed to assess the qualitative screening of Elytranthe parasitica for its secondary metabolites and also In-vitro evaluation of anti-inflammatory and antibacterial potential. The fresh leaf samples were collected and extracted with the help of a soxhlet extractor. The in-vitro anti-inflammatory potential was determined by protein denaturation assay and HRBC membrane stabilization assay, and evaluation of antibacterial properties by agar well diffusion assay. The results of the qualitative evaluation of phytoconstituents revealed a wide range of secondary metabolites. The methanolic leaf extracts of Elytranthe parasitic exhibited significant protein denaturation activity of (82.46 ± 1.37)% at 250 µg ml-1 concentration and showed significant membrane stabilization activity (65.57±2.60)% at 500 µg ml-1 concentration. It also shows good membrane stabilizations activity shows considerable antibacterial activity with the maximum inhibition zone against Xanthomonas campestris (18.16±0.44 mm) followed by Escherichia coli (15.33±0.88 mm), Staphylococcus aureus (11.16±0.44), and Salmonella typhi (10.66±0.66 mm) at higher concentrations. To conclude, it was found that Elytranthe parasitica (L.) Danser has a variety of secondary metabolites that have potent anti-inflammatory and antibacterial properties based on the experiments carried out.
Keywords:
Elytranthe parasitica, Loranthaceae, secondary metabolites, anti-inflammatory, antibacterialDOI
https://doi.org/10.25004/IJPSDR.2023.150308References
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