Formulation and Evaluation of herbal tablet containing hydro-alcoholic extract of Achyranthes aspera Linn. (Roots) used for the treatment of vaginal infection
Abstract
Vaginal infection include irritation, itching and swelling are very frequent and common among women due to various un-hygienic issues including a major fungus causing infection is Candida species. According to Ayurveda several herbs are used to cure women disorders, though there proper documentation and validation need to be established. It has increasingly deserved a special attention among the medical community. In spite of the presence of Candida species as a human commensal, alarming rates of local and systemic infections have been observed, varying from moderate to severe impact. The present investigation aims to formulate and evaluate herbal tablet containing hydro-alcoholic extract of Achyranthes aspera Linn. (Roots). Various batches F1 to F8 were prepared using different ratio of ingredients and were evaluated as per IP. The data obtained indicate that F7 have excellent results when compared with other formulation codes.
Keywords:
Vaginal infection, Achyranthes aspera, FormulationDOI
https://doi.org/10.25004/IJPSDR.2019.110406References
Lakshmi V, Gupta RK. Ayurvedic preparations and gynaecological disorders. International Journal of Ayurveda & Alternative Medicine. 2014; 5(2):10-14.
Dwivedi S, Tripathi R, Dwivedi SN. Ethno-medicinal plants used to treat gynecological disorders by tribal people of Madhya Pradesh, India. International Journal of Pharmacy and Life Sciences. 2010; 1(3): 160-169.
Palombo EA. Traditional medicinal plant extracts and natural products with activity against oral bacteria: potential application in the prevention and treatment of oral diseases. Evidence-Based Complementary and Alternative Medicine. 2011, Article ID 680354, 15.
Sher A. Antimicrobial activity of natural products from medicinal plants. Gomal Journal of Medical Sciences. 2009; 7(1): 72–78, 2009.
Rubió L, Motilva MJ, Romero MP. Recent advances in biologically active compounds in herbs and spices: a review of the most effective antioxidant and anti-inflammatory active principles. Critical Reviews in Food Science and Nutrition. 2013; 53(9): 943–953.
Dwivedi S. Status survey of medicinal plants wealth of Malwa region of Madhya Pradesh with special reference to conservation of vulnerable and endangered species. J. Econ. Taxon. Bot. 2009; 33(2): 443-452.
Harborne JB. Phytochemical methods, Chapman and Hall, 1984, Ist Edition, London.
Mishra US, Murthy PN, Pasa G, Mishra D. Formulation development and evaluation of herbal tablet containing methanolic extract of Butea frondosa, Int. J. of Inst. Pharm. and Life Sci. 2011 1(3):1-15.
Lachman L, Liberman HA, Kanig JL. The Theory and Practice of Industrial Pharmacy, 3rd ed., Varghese publishing House Bombay, 1999; 443-453.
Subrahmanyam CVS. Text Book of Physical Pharmaceutics, 2nd Edn. 2001, Vallabh Prakashan, New Delhi, pp. 253-261.
Aulton ME. Pharmaceutics: The Science of Dosage Form Design. 2nd ed. 2002, Churchill Livingstone, London, pp. 322-334.
Costa P, Lobo J, Manuel S. Modeling and comparison of dissolution profile. Eur. J. of Pharm. Sci. 2001; 13:123-133.
Dwivedi S. Development of standardization parameters of Guizotia abyssinica (L.f.) Cass with special reference to its pharmacological approaches, Ph.D., Thesis 2015, SGVU, Jaipur.
Published
Abstract Display: 1728 
PDF Downloads: 1354 
