BACOPA MONNIERA -A FUTURE PERSPECTIVE
Abstract
Bacopa moniera, a traditional Ayurvedic plant, used for centuries as a memory enhancing, anti-inflammatory, analgesic, antipyretic, sedative and antiepileptic agent. The plant, extract and isolated bacosides (the major active principles) have been extensively investigated in several laboratories for their different biological activities. In addition researchers have evaluated the anti-inflammatory, cardio tonic and other pharmacological effects of Bacopa monniera preparations/exracts. Therefore, in view of the important activities performed by this plant, research is an on going process over Bacopa monniera.
Keywords:
Bacopa monniera, Brahmi, Brama, ScrophulariaceaeDOI
https://doi.org/10.25004/IJPSDR.2009.010304References
1. Satyavati GV, Raina MK, Sharma M. Chemical investigation of Herpestis monniera Linn (Brahmi). Indian J Pharmacology1976; 21: 303-304.
2. Chunekar.KC, BhavPrakash Nighantu. Vol 372 Chaukhamba Bharti, Publications, Varanasi (Hindi translation). 1960
3. Barrett S.C.H, Strother J.L Taxonomy and natural history of Bacopa in California. Syst Bot 1978; 5: 408-419.
4. Mathew KM. The flora of Tamil Nadu and Carna Rapinat Herbarium St. Joseph’s College, Trichirapalli India, 1984
5. Chopra RN, Nayar L, Chopra IC. Glossary of Indian Medicinal Plants, Vol 32, Council of Scientific and Industrial Research, New Delhi 1956.
6. Sastri MS, Dhalla NS, Malhotra CL. Chemical investigation of Herpestis monniera Linn (Brahmi). Indian J Pharmacol 1959; 21: 303-304
7. Chatterji N, Rastogi RP, Dhar ML. Chemical examination of Bacopa monniera Wettst: parti-isolation of chemical constituents. India J Chem 1965; 3: 24-29.
8. Garay S, Mahato SB, Ohtani K, Yamaski K. Dammarane-type triterpenoid saponins from Bacopa monniera. Phytochemistry 1996a; 42: 815-820.
9. Chakravarty AK, Sarkar T, Nakane T, Kawahara N, Masuda K, Shiojima K. Bacopaside I and II: two pseudojujubogenin glycisides from Bacopa monniera, Phytochemistry 2001; 58: 553-556.
10. Chakravarty AK, Sarkar T, Nakane T, Kawahara N, Masuda K. New Phenylethanoid glycosides from Bacopa monniera. Chem Pharm Bull 2002; 50: 1616-1618.
11. Chakravarty AK, Garai S, Masuda K, Nakane T, Kawahara N. Bacopasides III-IVP; three new triterpenoid glycosides from Bacopa monniera. Chem Pharm Bull 2003; 51: 215-217.
12. Dahwan BN, Singh HK. Pharmacology of ayurvedic nootropic Bacopa monniera, Abstr, No NR 59. Int Conv Biol Psychiat Bombay, 1996
13. Bhattacharya SK, Ghoshal S. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study, Phytomedicine 1998; 5: 77-82.
14. Sumathy T, Subramanian S, Govidasamy S, Balakrishna KG. Protective role of Bacopa monniera on morphine induced hepatotoxicity in rats. Phytoether Res 2001; 15: 643-645.
15. Jain P, Khanna.NK, Trehan T, Pendse VK, Gohwani JL. Anti-inflammatory effects of an ayurvedic preparations,Brahmi Rasayan,in rodents. Indian J Exp Biol 1994; 32: 633-636.
16. Rao CHV, Sairam K, Goel RK. Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion. Indian J Physio Pharmacol 2000; 44: 435-441
17. Elangovan V, Govindasamy S, Ramamoorthy N, Balasubramanian K. In vitro studies on the anticancer activity of Bacopa monniera. Fitoterapia 1995; 66: 211-215.
18. Singh Akanksha, Singh SK. Evaluation of anti-fertility potential of Brahmi in male mouse Department of Zoology, Banaras Hindu University, Varanasi, U.P., Contraception vol 79, 2009, pp. 71-79.
19. Limpeanchob N, Jaipan S, Rattanakaruna S, Phrompittayarat W, Ingkaninan K. Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences and Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok65000,Thailand Journal of Ethnopharmacology 2008; 120: 112-117.
20. Viji V, Helen A. Inhibition of lipoxygenases and cyclooxygenase-2 enzymes by extracts isolated from Bacopa monniera (L.) Wettst Department of Biochemistry, University of Kerala, 2008.
21. Channa S, DarA S, Yaqoob M, Rahman,A. Anti-inflammatory activity of Bacopa monniera in rodents. J of Ethnopharmacol 2006; 104: 286-289.
22. Goel RK, Sairam K, Babu MD, Tavares IA, Raman A. In vitro evaluation of Bacopa monniera on anti-Helicobacter pylori activity and accumulation of prostaglandins. Phytomedicine 2003; 10: 523-527.
23. Russo A, Izzo AA, Borrelli F, Renis M, Vanella A. Free radical scavenging capacity and protective effect on DNA damage of Bacopa monniera L. Phytoether Res 2003a; 17:870-875.
24. Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacol Biochem Behave 2003; 75: 823-830.
25. Bose KC, Bose NK. Observations on the actions and uses of Herpestis monniera, J Indian Med Assoc 1931; 1: 60.
2. Chunekar.KC, BhavPrakash Nighantu. Vol 372 Chaukhamba Bharti, Publications, Varanasi (Hindi translation). 1960
3. Barrett S.C.H, Strother J.L Taxonomy and natural history of Bacopa in California. Syst Bot 1978; 5: 408-419.
4. Mathew KM. The flora of Tamil Nadu and Carna Rapinat Herbarium St. Joseph’s College, Trichirapalli India, 1984
5. Chopra RN, Nayar L, Chopra IC. Glossary of Indian Medicinal Plants, Vol 32, Council of Scientific and Industrial Research, New Delhi 1956.
6. Sastri MS, Dhalla NS, Malhotra CL. Chemical investigation of Herpestis monniera Linn (Brahmi). Indian J Pharmacol 1959; 21: 303-304
7. Chatterji N, Rastogi RP, Dhar ML. Chemical examination of Bacopa monniera Wettst: parti-isolation of chemical constituents. India J Chem 1965; 3: 24-29.
8. Garay S, Mahato SB, Ohtani K, Yamaski K. Dammarane-type triterpenoid saponins from Bacopa monniera. Phytochemistry 1996a; 42: 815-820.
9. Chakravarty AK, Sarkar T, Nakane T, Kawahara N, Masuda K, Shiojima K. Bacopaside I and II: two pseudojujubogenin glycisides from Bacopa monniera, Phytochemistry 2001; 58: 553-556.
10. Chakravarty AK, Sarkar T, Nakane T, Kawahara N, Masuda K. New Phenylethanoid glycosides from Bacopa monniera. Chem Pharm Bull 2002; 50: 1616-1618.
11. Chakravarty AK, Garai S, Masuda K, Nakane T, Kawahara N. Bacopasides III-IVP; three new triterpenoid glycosides from Bacopa monniera. Chem Pharm Bull 2003; 51: 215-217.
12. Dahwan BN, Singh HK. Pharmacology of ayurvedic nootropic Bacopa monniera, Abstr, No NR 59. Int Conv Biol Psychiat Bombay, 1996
13. Bhattacharya SK, Ghoshal S. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study, Phytomedicine 1998; 5: 77-82.
14. Sumathy T, Subramanian S, Govidasamy S, Balakrishna KG. Protective role of Bacopa monniera on morphine induced hepatotoxicity in rats. Phytoether Res 2001; 15: 643-645.
15. Jain P, Khanna.NK, Trehan T, Pendse VK, Gohwani JL. Anti-inflammatory effects of an ayurvedic preparations,Brahmi Rasayan,in rodents. Indian J Exp Biol 1994; 32: 633-636.
16. Rao CHV, Sairam K, Goel RK. Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion. Indian J Physio Pharmacol 2000; 44: 435-441
17. Elangovan V, Govindasamy S, Ramamoorthy N, Balasubramanian K. In vitro studies on the anticancer activity of Bacopa monniera. Fitoterapia 1995; 66: 211-215.
18. Singh Akanksha, Singh SK. Evaluation of anti-fertility potential of Brahmi in male mouse Department of Zoology, Banaras Hindu University, Varanasi, U.P., Contraception vol 79, 2009, pp. 71-79.
19. Limpeanchob N, Jaipan S, Rattanakaruna S, Phrompittayarat W, Ingkaninan K. Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences and Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok65000,Thailand Journal of Ethnopharmacology 2008; 120: 112-117.
20. Viji V, Helen A. Inhibition of lipoxygenases and cyclooxygenase-2 enzymes by extracts isolated from Bacopa monniera (L.) Wettst Department of Biochemistry, University of Kerala, 2008.
21. Channa S, DarA S, Yaqoob M, Rahman,A. Anti-inflammatory activity of Bacopa monniera in rodents. J of Ethnopharmacol 2006; 104: 286-289.
22. Goel RK, Sairam K, Babu MD, Tavares IA, Raman A. In vitro evaluation of Bacopa monniera on anti-Helicobacter pylori activity and accumulation of prostaglandins. Phytomedicine 2003; 10: 523-527.
23. Russo A, Izzo AA, Borrelli F, Renis M, Vanella A. Free radical scavenging capacity and protective effect on DNA damage of Bacopa monniera L. Phytoether Res 2003a; 17:870-875.
24. Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacol Biochem Behave 2003; 75: 823-830.
25. Bose KC, Bose NK. Observations on the actions and uses of Herpestis monniera, J Indian Med Assoc 1931; 1: 60.
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03-10-2009
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“BACOPA MONNIERA -A FUTURE PERSPECTIVE”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 1, no. 3, Oct. 2009, pp. 154-7, https://doi.org/10.25004/IJPSDR.2009.010304.
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Copyright (c) 2009 Shikha Srivastava, Nidhi Mishra, Upama Misra
This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
“BACOPA MONNIERA -A FUTURE PERSPECTIVE”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 1, no. 3, Oct. 2009, pp. 154-7, https://doi.org/10.25004/IJPSDR.2009.010304.
