IN-VITRO ANTIBACTERIAL EFFICACY OF SOLVENT EXTRACTS OF LEAVES OF BAUHINIA RACEMOSA LAM. (CAESALPINIACEAE) AGAINST ENTERIC BACTERIAL PATHOGENS
Abstract
Phytochemical screening of the plant leaves reveals the presence of carbohydrates, alkaloids, flavonoids, steroids, and tannins. Petroleum ether extract, chloroform extract, ethyl acetate extract and methanol extracts of leaves of Bauhinia racemosa Linn. were prepared and antibacterial activity were studied by disc diffusion method against certain enteric bacterial pathogens such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aerogenes, Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella typhi, Staphylococcus epidermidis and Proteus vulgaris. The Methanol extracts had wide range of antibacterial activity against enteric bacterial pathogens than the petroleum ether extract, where as ethyl acetate extract were slightly higher antibacterial activity than chloroform extract. Antibacterial activity of various extract of leaves of Bauhinia racemosa was carried in attempt to develop a new pharmaceutical drug from natural origin for prevention of enteric infection.
Keywords:
Antibacterial activity, Bauhinia racemosa, enteric bacterial pathogens.DOI
https://doi.org/10.25004/IJPSDR.2011.030107References
2. Kiritikar KR and Basu BD. Indian medicinal plants. 2nd edn. International Book Distribution Vol. III. Dehradun, 1987, pp.1664–1666.
3. Parekh J, Nair R, Chanda S. Preliminary screening of some folkloric plants from Western India for potential antimicrobial activity. Indian J Pharmacol. 2005; 37: 408-409.
4. Prakash A and Khosa RL. Chemical studies on Bauhinia racemosa. Current Science, 1976; 45: 705-707.
5. El-Khatiba AS and Khaleel AE. Evaluation of some pharmacological properties of different extracts of Bauhinia racemosa leaf and Bassia muricata whole plant. Bulletin of the Faculty of Pharmacy, Cairo University, 1995; 33: 59-65.
6. El-Hossary GA, Selim MA, Sayed AE and Khaleel AE. Study of the flavonoid content of Bassia muricata and Bauhinia racemosa. Bulletin of the Faculty of Pharmacy, Cairo University, 2000; 38: 93-97.
7. World Health Organization, 5 th Programme Report, Programme for control of diarrhoeal diseases, Geneva. WHO Bulletin, 1985; 63: 557-772.
8. Ballal M. Screening of medicinal plants used in rural folk medicine for treatment of diarrhea, 2005. Internet: http: // www.Pharmoinfo.net.
9. Khandelwal KR. Preliminary photochemical screening, in: Practical Pharmacognosy Techniques and Experiments, Edn. 8, Nirali Publication, Pune, 20011, pp. 49-156.
10. NCCLS (National Committee for Clinical Laboratory Standards), Performance Standards for antimicrobial susceptibility testing. 8th Informational Supplement. M100 S12. National Committee for Clinical Laboratory Standards, Villanova, Pa 2002.
Published
Abstract Display: 181 
PDF Downloads: 197 
