ANALGESIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF PAVETTA INDICA

Authors

  • D. K. Golwala C.U. Shah College of Pharmacy and Research, Opp. IBP Petrol pump, Surendranagar- Ahmedabad highway, Wadhwan363030, Gujarat, India
  • L. D. Patel SAL Institute of Pharmacy, Opp. Science City, Sola-Bhadaj Road, Ahmedabad, Gujarat, India
  • S. B. Bothara C.U. Shah College of Pharmacy and Research, Opp. IBP Petrol pump, Surendranagar- Ahmedabad
  • P. M. Patel B. M. Shah College of Pharmaceutical Education and Research, Modasa-383315, Gujarat, India
  • S. K. Vaidya C.U. Shah College of Pharmacy and Research, Opp. IBP Petrol pump, Surendranagar- Ahmedabad highway, Wadhwan363030, Gujarat, India
  • M. K. Raval Department of Pharmaceutical Sciences, Saurashtra University, Rajkot-360005, Gujarat, India

Abstract

The present study was designed to investigate Analgesic activity of ethanolic leaf extract of Pavetta indica, using hot plate method and tail clip method. Ethanolic extract was administered intraperitoneally at doses of 60 mg/kg and 80 mg/kg to Swiss albino mice and Wister rats. Ethanolic leaf extract of Pavetta indica showed significant (p<0.01) inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain. 

Keywords:

Pavetta indica, analgesic, hot plate and tail clip method.

DOI

https://doi.org/10.25004/IJPSDR.2009.010215

References

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Published

01-07-2009
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How to Cite

“ANALGESIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF PAVETTA INDICA”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 1, no. 2, July 2009, pp. 119-20, https://doi.org/10.25004/IJPSDR.2009.010215.

Issue

Volume 1, Issue 2, 2009

Section

Short Communication

Copyright (c) 2009 D. K. Golwala, L. D. Patel, S. B. Bothara, P. M. Patel, S. K. Vaidya, M. K. Raval

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

“ANALGESIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF PAVETTA INDICA”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 1, no. 2, July 2009, pp. 119-20, https://doi.org/10.25004/IJPSDR.2009.010215.