COMPARATIVE PHARMACOGNOSTIC, PHYSICOCHEMICAL AND PHYTOCHEMICAL STUDIES OF DIFFERENT SAMPLES OF PLUMBAGO ZEYLANICA L. ROOTS
Abstract
The objective of the present study is to evaluate the quality of the marketed and self collected samples of Plumbago zeylanica L. roots on the standardization parameters. This study is planned mainly to confirm changes with quality of drug. Now a day’s more demand of herbal drugs for disease treatment, lack of knowledge of proper methodology and availability are promoting the practices of adulteration and substitution. Thus, the standardization of the plant crude drugs is necessary to maintain their therapeutic efficacy. Comparative studies were carried out to evaluate the standards of P. zeylanica L. with emphasis on organoleptic evaluation, physicochemical and phytochemical analysis. Samples were procured from local market and self collected to determine the qualitative and quantitative variations. The result indicates that self collected sample showed significant results with comparison to marketed sample.
Keywords:
Plumbago zeylanica L., Physicochemical studies, Phytochemical screening, Standardization.DOI
https://doi.org/10.25004/IJPSDR.2017.090601References
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7. Dai Y, Hou LF, Chan YP, Cheng L, Bur PPH. Inhibition of immediate allergic reactions by ethanol extract from Plumbago zeylanica stems. Biol Pharm Bull. 2004; 27(3): 429–432.
8. Bopaiah CP, Pradhan N. Central nervous system stimulatory action from the root extract of Plumbago zeylanica in rats. Phytotherapy Research. 2001; 15(2):153–6
9. Sunil C, Duraipandiyan V, Agastian P, Ignacimuthu S, Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L. root and its effect on GLUT4 translocation in streptozotocin induced diabetic rats. Food Chem Toxicol. 2012; 50(12): 435–446.
10. Kanchana N, Sadiq MA. Hepatoprotective effect of Plumbago zeylanica on paracetamol induced liver toxicity in rats. International Journal of Pharmacy and Pharmaceutical Sciences. 2011; 3(1):151-154.
11. Pendurkar SR, Mengi SA. Antihyperlipidemic effect of aqueous extract of Plumbago zeylanica roots in diet-induced hyperlipidemic rat. Pharm Biol. 2009; 47(10): 1004–1010.
12. Wang YC, Huang TL. Anti-Helicobacter pylori activity of Plumbago zeylanica L. FEMS Pathogens and Disease. 2005; 43(3): 407–412
13. Mishra BB, Gour JK, Kishore N, Singh RK, Tripathi V, Tiwari V K. An antileishmanial prenyloxy-naphthoquinone from roots of Plumbago zeylanica. Nat Prod Res. 2013; 27(4-5): 480–485
14. Premkumari P, Rathinam K, Santhakumari G. Antifertility activity of plumbagin. Indian J Med Res. 1977; 65(6): 829-838.
15. Dhar SK, Rao PG. Hormonal profile of plumbagin. Fitoterapia. 1995; 66(5): 442-446.
16. Gebre-Mariam T, Neubert R, Schmidt PC, Wutzler P, Schmidtke M. Antiviral activities of some Ethiopian medicinal plants used for the treatment of dermatological disorders. J Ethnopharmacol. 2006; 104(1-2): 182–187.
17. Wang YC, Huang TL. High-performance liquid chromatography for quantification of plumbagin an anti-Helicobacter pylori compound of Plumbago zeylanica L. J Chromatogr A. 2005; 1094(1-2): 99-104.
18. Zaidi SFH, Yamada K, Kadowaki M, Khan U, Sugiyama T. Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori. J Ethnopharmacol. 2009; 121(2): 286–291.
19. Sharma I, Gusain D, Dixit VP. Hypolipidaemic and antiatherosclerotic effects of plumbagin in rabbits. Indian J Physiol Pharmacol. 1991; 35(1): 10-14.
20. Wallis TE. Text Book of Pharmacognosy. CBS publishers and Distributors, Delhi. 1989.
21. Evans WC. Trease and Evans- Pharmacognosy. WB Sacenders Company Ltd. London. 1996.
22. WHO. Quality Control for Medicinal Plant Material. AITBS Publishers, New Delhi. 1998.
23. WHO. Quality Control Methods for Medicinal Plant Material. Geneva. 1992.
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25. Khandelwal KR. Practical Pharmacognosy. Nirali Publication, Pune. 2007.
2. Kirtikar KR, Basu BD. Indian Medicinal Plants. Sri Satguru Publications, New Delhi, 2000.
3. Ayurvedic Pharmacopoeia of India, Government of India, Department of AYUSH, 1999, 29.
4. Thanigavelan V, Venkatachalam K, Venkatachalam L, Natarajan S, Murugan PK, Savarimuthu JA. Hydroalcoholic extract of Plumbago zeylanica Linn root bark exhibit analgesic and anti-inflammatory activities in experimental rat models. Am J Pharm Health Res. 2014; 2(4): 209–221.
5. Simonsen HT, Nordskjold JB, Smitt UW, Nyman U, Palpu P, Joshi P, Varughese G. In vitro screening of Indian medicinal plants for antiplasmodial activity. J Ethnopharmacol. 2001; 74(2): 195–204
6. Chinsembu KC. Plants as antimalarial agents in Sub-Saharan Africa. Acta Tropica. 2015; 152: 32-48
7. Dai Y, Hou LF, Chan YP, Cheng L, Bur PPH. Inhibition of immediate allergic reactions by ethanol extract from Plumbago zeylanica stems. Biol Pharm Bull. 2004; 27(3): 429–432.
8. Bopaiah CP, Pradhan N. Central nervous system stimulatory action from the root extract of Plumbago zeylanica in rats. Phytotherapy Research. 2001; 15(2):153–6
9. Sunil C, Duraipandiyan V, Agastian P, Ignacimuthu S, Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L. root and its effect on GLUT4 translocation in streptozotocin induced diabetic rats. Food Chem Toxicol. 2012; 50(12): 435–446.
10. Kanchana N, Sadiq MA. Hepatoprotective effect of Plumbago zeylanica on paracetamol induced liver toxicity in rats. International Journal of Pharmacy and Pharmaceutical Sciences. 2011; 3(1):151-154.
11. Pendurkar SR, Mengi SA. Antihyperlipidemic effect of aqueous extract of Plumbago zeylanica roots in diet-induced hyperlipidemic rat. Pharm Biol. 2009; 47(10): 1004–1010.
12. Wang YC, Huang TL. Anti-Helicobacter pylori activity of Plumbago zeylanica L. FEMS Pathogens and Disease. 2005; 43(3): 407–412
13. Mishra BB, Gour JK, Kishore N, Singh RK, Tripathi V, Tiwari V K. An antileishmanial prenyloxy-naphthoquinone from roots of Plumbago zeylanica. Nat Prod Res. 2013; 27(4-5): 480–485
14. Premkumari P, Rathinam K, Santhakumari G. Antifertility activity of plumbagin. Indian J Med Res. 1977; 65(6): 829-838.
15. Dhar SK, Rao PG. Hormonal profile of plumbagin. Fitoterapia. 1995; 66(5): 442-446.
16. Gebre-Mariam T, Neubert R, Schmidt PC, Wutzler P, Schmidtke M. Antiviral activities of some Ethiopian medicinal plants used for the treatment of dermatological disorders. J Ethnopharmacol. 2006; 104(1-2): 182–187.
17. Wang YC, Huang TL. High-performance liquid chromatography for quantification of plumbagin an anti-Helicobacter pylori compound of Plumbago zeylanica L. J Chromatogr A. 2005; 1094(1-2): 99-104.
18. Zaidi SFH, Yamada K, Kadowaki M, Khan U, Sugiyama T. Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori. J Ethnopharmacol. 2009; 121(2): 286–291.
19. Sharma I, Gusain D, Dixit VP. Hypolipidaemic and antiatherosclerotic effects of plumbagin in rabbits. Indian J Physiol Pharmacol. 1991; 35(1): 10-14.
20. Wallis TE. Text Book of Pharmacognosy. CBS publishers and Distributors, Delhi. 1989.
21. Evans WC. Trease and Evans- Pharmacognosy. WB Sacenders Company Ltd. London. 1996.
22. WHO. Quality Control for Medicinal Plant Material. AITBS Publishers, New Delhi. 1998.
23. WHO. Quality Control Methods for Medicinal Plant Material. Geneva. 1992.
24. Kokate CK. Practical Pharmacognosy. Vallabh Prakashan, New Delhi, 1994.
25. Khandelwal KR. Practical Pharmacognosy. Nirali Publication, Pune. 2007.
Published
01-11-2017
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“COMPARATIVE PHARMACOGNOSTIC, PHYSICOCHEMICAL AND PHYTOCHEMICAL STUDIES OF DIFFERENT SAMPLES OF PLUMBAGO ZEYLANICA L. ROOTS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 9, no. 6, Nov. 2017, pp. 286-90, https://doi.org/10.25004/IJPSDR.2017.090601.
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How to Cite
“COMPARATIVE PHARMACOGNOSTIC, PHYSICOCHEMICAL AND PHYTOCHEMICAL STUDIES OF DIFFERENT SAMPLES OF PLUMBAGO ZEYLANICA L. ROOTS”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 9, no. 6, Nov. 2017, pp. 286-90, https://doi.org/10.25004/IJPSDR.2017.090601.
